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high certainty of the evidence

— The research provides a very good indication of the likely effect of a treatment. The likelihood that the actual effect will be substantially different from this is low


high confidence in the effect estimate, high quality of the evidence, high strength of the evidence

Full explanation:

High certainty of the evidence means that the likelihood is low that the effect will be different enough from what the research found that it might affect a decision.

Judgements about the certainty of the evidence are based on factors that reduce the certainty (risk of bias, inconsistency, indirectness, imprecision, and reporting bias), and factors that increase the certainty, such as dramatic treatment effects.

There is high certainty of the evidence when there are few or no factors that reduce the certainty of the evidence, or when there are factors, such as dramatic treatment effects, that increase the certainty of the evidence.

See also:

certainty of the evidence  ·  GRADE

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